In 2019, a new species of Neopestalotiopsis was reported to cause significant damage in strawberry fields in Florida. Since then, this disease has been found in most southeastern states, including Virginia and Delaware. Molecular identification has revealed that more than one Neopestalotiopsis species is pathogenic to strawberry plants and can cause symptoms on leaves (leaf spot), fruit (fruit rot), and crown (crown rot) of strawberry plants. We would like to share the current knowledge on the biology of Neopestalotiopsis spp. and management practices that could partially suppress Neopestalotiopsis fruit rot in strawberries.